Iodine-125 seed implantational radiotherapy combined with transcatheter arterial chemoembolization for hepatocellular carcinoma
- VernacularTitle:粒子植入放疗联合肝动脉化疗栓塞治疗肝癌的临床研究
- Author:
Kaiyun CHEN
;
Guoan XIANG
;
Hanning WANG
;
Fanghan XIAO
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Iodine-125 seed implantation radiotherapy;
Transcatheter arterial chemoembolization
- From:
Chinese Journal of Radiation Oncology
2005;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
90 Gy . Tumor irradiation dose, the umber of tumor and liver cirrhosis were identified by Cox-regression analysis as independent predictors for survival. Two patients experienced CTC grade 1 acute hepatic toxicity and three patients experienced grade 3 acute hepatic toxicity. Two patients developed RILD. Nine patients experienced RTOG grade 1 acute gastrointestinal complication and one patient experienced acute gastrointestinal bleeding. Five patients experienced RTOG grade 1 leucopenia and five patients experienced grade 2 leucopenia. Conclusion Iodine-125 seed local radiotherapy combined with TACE is safe and effective for HCC. It is worth of further dose escalation study.
