The different-dose simvastatin's effect on the platelet activity after the elderly patients' treatment by PCI
- VernacularTitle:不同剂量辛伐他汀对老年冠状动脉介入术后血小板活化的影响
- Author:
Xu LIANG
;
Zhijun HUANG
;
Lulu HUANG
- Publication Type:Journal Article
- Keywords:
Platelet activity;
PCI;
Simvastatin
- From:
Chinese Journal of Practical Internal Medicine
2006;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the serum level of the CD62p,CD63 which indicates the platelet activity of the elderly patients treated by different-dose simvastatin after PCI.Methods Sixty-eight patients with acute coronary syndrome post PCI were randomly divided into 20 mg/d simvastatin group(36 patients)and 40 mg/d simvastatin group(32 patients).We examined the patient's blood CD62p,CD63 levels on the day before the treatment of PCI in both groups.Then all of the patients in both groups received different-dose simvastatin treatment(20mg/d or 40 mg/d qn po);we observed the results again after four weeks in both groups,and compared the results.Results The patients' blood CD62p,CD63 levels decreased significantly after the treatment of simvastatin in both groups(P
