The Correlation of the Polymorphisms of CETP Gene with the Natural Longevity in Uygur Population
- VernacularTitle:CETP基因TaqIB及I405V多态性与新疆维吾尔族自然长寿的关联
- Author:
Ling SUN
;
Qun XU
;
Zuheng CHENG
;
Changchun QIU
- Publication Type:Journal Article
- Keywords:
CETP;
Polymorphism;
Longevity;
Uygur population
- From:
Journal of Medical Research
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relation ship between two polymorphisms within the CETP gene,TaqIB and I4O5V,and natural longevity in the Uygur population.Methods 191 healthy individuals over 90 years old and 53 control individuals who died before their 75 years were recruited.The polymorphisms within CETP gene,TaqIB and I4O5V,were genotyped by PCR-RFLP and PCR-Sequencing.Results There were no difference in the genotypes and alleles distribution of two polymorphisms within the CETP gene between longevity group and control group.Conclusions There was no correlation between the polymorphisms within CETP gene,TaqIB and I4O5V,and natural longevity of Uygur population in Hetian.
