Detection of Nanobacteria in Blood of Patients with Chronic Hepatopathy by PCR Method
- VernacularTitle:聚合酶链反应检测肝病患者血液中纳米细菌的研究
- Author:
Guoqiang LOU
;
Mingli ZHU
;
Ying LUO
;
Chaodan LI
;
Xiaoyu LI
;
Jun ZHOU
;
Shourong LIU
- Publication Type:Journal Article
- Keywords:
Nanobacteria;
Polymerase chain reaction;
Chronic hepatopathy
- From:
Journal of Medical Research
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the infection status of nanobacteria on patients of chronic hepatopathy and hepatocellular carcinoma,and evaluate the clinical value of PCR.Methods In sera of 68 cases of chronic hepatitis B(CHB),56 chronic severe hepatitis B(CSHB),66 cirrhosis of liver(CL)and 23 hepatocellular carcinoma(HCC),nanobacteria were detected by immunohistochemistry stain(IHC),Transmission Electron Microscopy(TEM)and polymerase chain reaction(PCR),compared with 40 healthy people.Results The positive rates of PCR were 27.69%,50.00%,61.29%,52.38% and 5.00% in patients with CHB,CSHB,CL,HCC and normal control respectively(P
