Effects of Valsartan and Benazepril on Albuminuria in Diabetic Nephropathy
- VernacularTitle:缬沙坦和贝那普利治疗糖尿病肾病蛋白尿疗效比较
- Author:
Lianjun DOU
;
Qingqiang WU
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathy;
Valsartan;
Benazepril;
Therapy
- From:
Journal of Medical Research
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
300mg/d)were randomly divided into two groups:①Val group consisted of 20 cases(8M/12F),treated with Val 80~160mg/day.②Ben group 20 cases(9M/11F),treated with Ben 10~30mg/d.A goal of blood pressure(BP)control was 130/80mmHg or less in the two groups.Treatment period lasted for 8 weeks.The levels of UAE were measured by radioimmunoassay before and after treatment.We also measured Bp,fasting blood glucose,glycosylated hemoglobulin.Results After treatment of 8 weeks,Bp values in the two groups declined significantly compared with the pretreatment levels(P0.05).The levels of UAE in the two groups decreased significantly in comparison with pretreatment(P0.05).Val group seems to have lower adverse drug reaction rate.Conclusions The results indicate that Val has similar effects on reducing UAE in DN compared with Ben.And Val has fewer side effects.
