HISTOGENESIS OF THE HUMAN LIVER
- VernacularTitle:胎儿肝脏的组织发生
- Author:
Suyun HE
- Publication Type:Journal Article
- From:
Acta Anatomica Sinica
1954;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
Liver specimens from 41 human fetuses of about the 7 th week gestation tonewborn were studied.The liver tissues were fixed in proper fixatives and stainedwith H.E.,Unna's method for RNA,McManus PAS reaction for glycogen,Gomori'sCa-Co method for AlP and Altmann's method for mitochondria.In 7-week old embryo,the liver shows trabeculae of recognizable liver cells andsinusoids only.The ingrowth of connective tissue about the portal vein is observedduring the 8th week.The formation of lobular arrangment in adult liver startsfrom 9～12 weeks.The inter-and intra-lobular bile ducts derived from the peripor-tal limiting plate at the same period.The hepatic cells of the 8th week embryo arrange in plate form.The hepaticplate is plastic and changes in various thickness depending upon the size of theadjacent sinusoids.The cytoplasm of embryonic hepatic cell is rich in RNA,glycogen and mitochon-dria and is weak in AlP activity.However zonation does not appear in liverlobules during fetal life.
