Effect of glutamine on Hsp70 expression and immune in patients with acute cerebral infarction
- VernacularTitle:谷氨酰胺对脑梗死病人热休克蛋白70表达及免疫功能的影响
- Author:
Huiwei HE
;
Jingsong ZHANG
;
Fuxi SUN
;
Zhiqiang GAO
- Publication Type:Journal Article
- Keywords:
Cerebral infarction;
Glutamine;
Heat shock protein 70
- From:
Parenteral & Enteral Nutrition
2004;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effects of glutamine on heat shock protein 70(Hsp70) expression and immune in patients with acute cerebral infarction.Methods: 60 patients with acute cerebral infarction were randomly divided into 2 groups,the control group(n=30) and the glutamine group.Patients in glutamine group were supplemented intravenously with alanyl-glutamine during 24 hours after hospitalization.Other treatments were the same as in the control group.Serum Hsp70 concentrations,immune parameters,and infection rates were compared.Results: The serum Hsp70 level,the immune globulin level,the CD4+ cell and CD4+/CD8+ in the glutamine group were significantly higher than those in the control group(P