C-reactive protein in non-smokers,ex-smokers,and smokers with COPD experiencing exacerbations
- VernacularTitle:吸烟对慢性阻塞性肺疾病急性加重期患者C-反应蛋白的影响
- Author:
Zhougui LING
;
Wei LIU
;
Lianqiang JIANG
- Publication Type:Journal Article
- Keywords:
Pulmonary disease,chronic obstructive;
C-reactive protein;
Acute exacerbation
- From:
Chinese Journal of Practical Internal Medicine
2006;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the difference of C-reactive protein(CRP)in non-smokers,ex-smokers,and smokers with chronic obstructive pulmonary disease experiencing exacerbations(AECOPD)and the relation of blood white cells in order to study the role of smoking to CRP.Methods Five hundreds and sixty-eight patients with AECOPD were enrolled in the retrospective case-study.Patients were divided into three groups:non-smokers,ex-smokers,and smokers.CRP and WBC were measured to compare their changes.Results Serum CRP levels of three groups were 5.7 mg/L,5.6 mg/L and 5.8 mg/L,respectively;there was no significant difference among them;cigarette smoking had no effect on the raised serum CRP levels;similarity,WBC of theirs were 8.6?109/L,9.1?109/L and 8.5?109/L,respectively;there was also no significant difference among them(P=0.299).There was little relationship between CRP and WBC.Conclusion Serum CRP levels in non-smokers,ex-smokers,and smokers with AECOPD are raised and are independent of cigarette smoking.Maybe CRP is related to infection.