Modulation of HERG/I_(Kr) in pathological condition and effect of traditional chinese medicine on HERG/I_(Kr)
- VernacularTitle:病理状态HERG/I_(Kr)通道角色及中药干预的研究
- Author:
Yuhong ZHOU
;
Baofeng YANG
;
Baoxin LI
- Publication Type:Journal Article
- Keywords:
HERG/IKr channel;
pathology;
traditional chinese medicine
- From:
Chinese Pharmacological Bulletin
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
HERG/IKr plays an important role in repolarization of cardiac action potential. In pathological condition such as cardiac ischemia, congestive heart failure and myocardial hypertrophy, the density and kinetic properties of HERG/IKr will change. This review is about modulation of HERG/IKr in pathological condition and effect of traditional chinese medicine on HERG/IKr.
