A Case of Type I Renal Tubular Acidosis Associated with Graves' Disease and Sjogren' s Syndrome.
- Author:
Eun Ju CHO
1
;
Paek Sun KIM
;
Cheol Whee PARK
;
Sung No YUN
;
Dong Chan JIN
;
Yoon Sik CHANG
;
Byung Kee BANG
Author Information
1. Department of Internal Medicine, Catholic University Medical College, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Type 1 RTA;
Sjogren' s syndrome;
Graves' disease
- MeSH:
Acidosis;
Acidosis, Renal Tubular*;
Adult;
Autoimmune Diseases;
Biopsy;
Female;
Graves Disease*;
Humans;
Hypesthesia;
Muscle Weakness;
Palate;
Thyroid Function Tests
- From:Korean Journal of Nephrology
1997;16(3):572-577
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Classic distal renal tubular acidosis(type 1 RTA) is a hypokalemic, hyperchloremic metabolic acidosis due to selective defect in distal acidification. Type 1 RTA may be associated with genetic(usually autosomal dominant) or autoimmune disease, drugs and toxin and various tubulointerstitial diseases. This case report describes a 27 year-old female patient with distal RTA, Sjogren' s syndrome and Graves' disease the first case. She had been suffered from muscle weakness and peripheral numbness and was found to have low serum potassium(1.6mEq/L). She was revealed to have 1) distal RTA by NaHCO3 loading test 2) Sjogren' s syndrome by Schirmer' s test and palate biopsy and 3) Graves' disease by exophthalmometry and autoantibody test, thyroid function test. This is the first case as far as I search that report the association of distal RTA, Sjogren' s syndrome, and Graves' disease caused by autoimmune mechanism.
