Clinical analysis of non-Hodgkin's lymphoma treated by high dose MTX,autologous peripheral stem cell transplantation and biotherapy for 67 cases
- VernacularTitle:大剂量化疗 自体外周血干细胞移植 生物治疗序贯疗法对67例非霍奇金淋巴瘤的疗效观察
- Author:
Xinghua CHEN
;
Xi ZHANG
;
Lei GAO
- Publication Type:Journal Article
- Keywords:
Lymphoma,non-Hodgkin;
High dose MTX;
Autologous peripheral stem cell transplantation;
Biotherapy
- From:
Chinese Journal of Practical Internal Medicine
2006;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of non-Hodgkin's lymphoma(NHL)treated by high does MTX,autologous peripheral stem cell transplantation and biotherapy for 67 cases.Methods Sixty-seven NHL patients from June,2003 to March,2007 were treated by three times HD-MTX,APBSCT and biotherapy of IL-2.Results There were 36 cases(87.8%)in complete relase(CR)period;5 cases(12.2%)in relapse(RE)period and 1 patient(2.4%)died in CR group;in PR group,there were 15 cases(57.7%)in CR period;11 cases(42.3%)in RE period and 5 patients(19.2%)died.Conclusion These preliminary results suggest that the therapy can be performed safely.It is an efficacious therapeutic measure for the patients with non-Hodgkin's lymphoma.
