The clinical study of non-T-depleted human leukocyte antigen mismatched hematopoietic stem cell transplants with total body irradiation for the treatment of leukemia
- VernacularTitle:含全身照射预处理方案行HLA不相合非去T造血干细胞移植治疗白血病8例临床分析
- Author:
Yu WANG
;
Lanping XU
;
Daihong LIU
- Publication Type:Journal Article
- Keywords:
Hematopoietic stem cell transplants;
Leukemia;
HLA mismatch;
Total body irradiation
- From:
Chinese Journal of Practical Internal Medicine
2006;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
20.0?109/L was day 13(11~21).All the patients got engraftment successfully and attained CR.Acute Ⅰ~Ⅱ GVHD occurred in 5 patients,no acute Ⅲ~Ⅳ GVHD occurred and extensive chronic GVHD did in 2 patients.All the patients were alive and only one patient relapsed after 3~53 months follow-up.Conclusion TBI-based conditioning regimen appears to be safe and effective for non-T-depleted HLA mismatched hemotopoietic stem cell transplants,especially for high-risk and second transplant patients.
