The Hemolytic Uremic Syndrome Associated with Periappendiceal Abscess.
- Author:
Young Su KIM
1
;
Suk Young KIM
;
Sung Bae MOON
;
Sung Ro YUN
;
Young Suk LEE
;
Hyung Wook KIM
;
Jong Min LEE
;
Dong Chan JIN
;
Byung Kee BANG
Author Information
1. Department of Internal Medicine, Catholic University Medical College, Korea.
- Publication Type:Case Report
- Keywords:
Hemolytic uremic syndrome;
Periappendiceal abscess
- MeSH:
Abdomen, Acute;
Abscess*;
Acute Kidney Injury;
Adult;
Anemia;
Anemia, Hemolytic;
Appendectomy;
Bacteria;
Creatinine;
Diagnosis;
Drainage;
Hemolysis;
Hemolytic-Uremic Syndrome*;
Humans;
Infant;
Korea;
Male;
Plasma Exchange;
Renal Dialysis;
Thrombocytopenia
- From:Korean Journal of Nephrology
1997;16(3):603-606
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The hemolytic uremic syndrome (HUS) is clinically characterized by microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. The unique cause has not been determined but some bacteria such as E. coli was regarded as the causative agent of HUS in infant. A 30-year-old male patient was admitted due to acute abdomen. In operating field, the periappendiceal abscess was found, so the appendectomy with the drainage of abscess was performed. Initial hemoglobin level was 16.2g/dL but abruptly developed anemia (12.6g/dL) and thrombocytopenia (27000/mm3) was detected at hospital day 3. The urinary outflow was totally absent, the serum creatinine was 12.8mg/dL and the LDH was 3,650IU/L. The peripheral blood smear showed strong evidence of microangiopathic hemolysis. We performed total plasma exchange and hemodialysis under the diagnosis of HUS. The patient's renal function was markedly improved and the last creatinine was 1.9mg/dl. To our knowledge, this is the first report of HUS associated with periappendiceal abscess in Korea. We present a case and the review of literature.