Comparison of the five models on experimental hyperlipidemia rats
- VernacularTitle:大鼠实验性高脂血症五种造模方法的比较
- Author:
Dong ZHANG
;
Haijun WU
;
Shiping CHEN
;
Kang YING
;
Yumei YANG
- Publication Type:Journal Article
- Keywords:
hyperlipidemia;
rat;
make model
- From:
Chinese Pharmacological Bulletin
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To select the ideal experimental rats model for research on prevention and treatment of Hyperlipidemia.Methods Five prescriptions on experimental hyperlipidemia-rats were selected and emulsion was made.At 10、20、30 d blood samples were taken from ocular orbit and content of CHO、 LDL、 HDL 、TG in the serum were measured.Results Four of the five prescriptions could lead to the disorder of lipid metabolism at different levels.Conclusion An ideal experimental rats model of hyperlipidemia can be made if bile salt and propylthiouracil are conbined to add to the fat emulsion of lard and cholesterol.
