Effects of(S,S)ZX-5 on gene expression of eNOS in ECV304
- VernacularTitle:NO释放调控剂(S,S)ZX-5对eNOS mRNA转录与eNOS蛋白表达的影响
- Author:
Hongying LIN
;
Quanzhan CHEN
;
Weiqiang WANG
;
Zilong SHEN
;
Yihua ZHANG
- Publication Type:Journal Article
- Keywords:
(S,S) ZX-5;
eNOS;
NO;
AMD
- From:
Chinese Pharmacological Bulletin
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To investigate the effects of(S,S)ZX-5 and(R,R)ZX-5 on eNOS mRNA and protein levels.Methods Cell culture was used for the experiments in vitro.The effects of eNOS mRNA were investigated by RT-PCR.The effects of eNOS protein levels were investigated by Western blot.Results(S,S)ZX-5 in concentration of 30 mg?L-1 up-regulated eNOS expressions at protein and mRNA levels significantly in cultured ECV304(P
