Analysis on Immune Effect of 10 Microgramme Recombinant Chinese Hamster Ovary (CHO) Cell HB Vaccine in Adults
- VernacularTitle:成人10?g重组(CHO细胞)乙肝疫苗免疫效果分析
- Author:
Yifeng ZHANG
;
Jie CHEN
;
Nanyan PAN
- Publication Type:Journal Article
- Keywords:
Recombinant chinese hamster ovary (CHO) cell;
Hepatitis B vaccine;
Adult immunization;
Analysis on effect
- From:
Journal of Medical Research
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore immune effects of HB vaccine and relative strategies of controlling hepatitis B in adults of different ages, genders, and different anti-HBs levels before immunization. Methods In Shaoxing city, 1055 healthy adults aged 18 to 50 with HBsAg negative were randomly selected and inoculated with 10?g/ml indigenous CHO HB vaccine according to the programme of 0,1,6 months. Results 835 adults completed the whole programme, and the total immunization coverage rate was 85.12%. Before and after immunization,the positive rates of anti-HBs were 52.10% and 98.44% respectively, and anti-HBsGMT rose from 14.32mU/ml to 413.98mU/ml. For the two groups, anti-HBsGMT=0 and 0
