The Changes of Hormones in the Model of Splennic Asthenia Complicating Gastric Ulcer
- VernacularTitle:脾气虚胃溃疡证病结合模型甲状腺组织降钙素研究
- Author:
Bairong LU
;
Jie LIAN
;
Haiyan ZHANG
;
Juan DU
;
Xiuqin WANG
;
Qingfeng MENG
- Publication Type:Journal Article
- Keywords:
Splennic asthenia;
Gastric ulcer;
Thyroid gland;
Calcitonin immunohistochemist
- From:
Journal of Medical Research
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To probe the changes of hormones in the model of splennic asthenia complicating gastric ulcer, and reveal the relation between thyroid gland and splennic asthenia gastric ulcer. Methods Building model of splennic asthenia complicating gastric ulcer in rats, treatment them in plus sijunzi decoction ,selecting rats with typical gastric ulcer four days after and rats with the ulcer healing basically fourteen days after building models, then the rats were divided into four groups, the model group, the treatment group, spontaneous recovery group and the control group. With immunohistochemical stain , the OD values of enzymes were analyzed with image analysis, and were analyzed statistically. Results Compare with control gronp ,4 model and 14 modelIn rats the thyrocalcitonin secretion of thyroid parafollicular decreased, Compared with 14 day control indexes in the treatment group recovered, but in the spontaneous recovery group all indexes didn’t change obviously. Conclusions In the model of splennic asthenia complicating gastric ulcer, some injury can occur on thyroid gland ,and this also promote gastric ulcer development. plus sijunzi decoction has some treating action.