Level and clinical value of the plasm IL-11 and soluble gp130 in the patients with acute leukemia during the treatment of the induced remission
- VernacularTitle:白介素-11及可溶性糖蛋白130在急性白血病诱导缓解过程中的变化及其意义
- Author:
Qiurong ZHANG
;
Depei WU
;
Miao MIAO
- Publication Type:Journal Article
- Keywords:
Interleukin-11;
Sgp130;
RhIL-11;
Acute Leukemia
- From:
Chinese Journal of Practical Internal Medicine
2006;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the levels and the significance of IL-11 and sgp130 in the treatment of newly-diagnosed acute leukemia(AL)during the treatment of the induced remission,and to evaluate the curate effect of rhIL-11 on AL.Methods The levels of IL-11 and sgp130 in patients with AL were determined by ELISA respectively before treatment and after completing remission(CR).1.5 mg of rhIL-11 was injected subcutaneously,once a day,continuously for 14 days as one course,of treatment time 1～2 courses as total.Results Plasm IL-11 level in AL patients was significantly lower than normal(P
