Effect of non-invasive positive pressure ventilation in treatment of COPD at acute exacerbation phase combined with typeⅡrespiratory failure in 53 patients
- VernacularTitle:无创正压通气治疗慢性阻塞性肺疾病急性加重期合并呼吸衰竭的临床观察
- Author:
Hongjun WANG
;
Hongbing LI
;
Pingfei WANG
;
Xueman ZHANG
- Publication Type:Journal Article
- Keywords:
chronic obstructive pulmonary disease at acute exacerbation phase;
respiratory failure;
non-invasive positive pressure ventilation
- From:Journal of Third Military Medical University
2003;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effect of non-invasive positive pressure ventilation(NIPPV) in the treatment of chronic obstructive pulmonary disease at acute exacerbation phase(AECOPD) combined with typeⅡrespiratory failure.Methods Fifty-three patients of therapeutic group were treated with NIPPV,as well as conventional therapeutic managements,such as antibiotic,pacifying gasp,eliminating phlegm,taking respiratory stimulants,and receiving continual low-flow oxygen.Whereas,53 controls only received conventional intervention.Results There was no significant difference between the 2 groups before the treatment,but significance was found in pH value,PaCO2,PaO2,HR and RR in them.The therapeutic group showed significantly improvement in PaCO2,RR and PaO2 compared with control group.Conclusion NIPPV intervention can effectively lower PaCO2 and RR,improve PaO2,shorten the course of hospitalization.
