Study on serum variation of liver cirrhosis patients with spontaneous peritonitis and cytokines in ascites
- VernacularTitle:肝硬化自发性腹膜炎患者细胞因子水平的变化
- Author:
Jianhua ZHOU
- Publication Type:Journal Article
- Keywords:
Liver cirrhosis;
Peritonitis;
Cytokines
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study on serum variation of liver cirrhosis patients with spontaneous peritonitis and cytokines in ascites caused by gram-positive bacteria or by gram-negative bacteria,so as to instruct clinical usage of antibiotics.Methods 60 cases of liver cirrhosis were carried out routine test to distinguish between exudative aseites and transudative ascites.At the same time,notric oxide(NO),tumor necrosi factor-?(TNF-?),LPS were tested in the serum and ascites of all patients with liver cirrhosis ascites.Results NO,TNF-?,LPS levels in the serum and as- cites of the exudative ascites patients with liver cirrhosis were obviously higher than those in the serum and ascites of transudate ascitcs patients with river cirrhosis.NO,TNF-?,LPS levels in ascites infected by gram-positive bacteria were obviously higher than those by gram-negative bacteria.Conclusion Test of NO,TNF-?,LPS in the serum and ascites of the patients with liver cirrhosis ascites can help to distinguish between exudative ascites and transudate as- cites,and distinguish between spontaneity peritonitis infected by gram-positive bacteria and by gram-negative bacteria so as to instruct clinical usage of drugs.
