Study of relationship between cervical cancerous and cervical intraepithelial neoplasia and HPV infection
- VernacularTitle:宫颈上皮内瘤病变与人乳头状瘤病毒感染
- Author:
Zhiliang GUO
- Publication Type:Journal Article
- Keywords:
Cervical intraepithelial neoplasia;
Papillomavirus,human;
Cervix neoplasms;
Oligonucleotide array sequence analysis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the relationship between cervical cancerous and precancerous lesions and human papilloma virus(HPV) infection.Methods 158 female patients with abnormal pap smears underwent colpo- scopically directed biopsies and hybrid captureⅡtest.Results HPV infection was distributed in 8.7 % of cervitis, in 34.7 % of low-grade squamous intraepithelial lesion(LSIL) ,in 68.9 % of high-grade squamous intraepithelial le- sion(HSIL) and in 83.3 % of cervical cancer.Conclusion HPV infection was correlated with cervical(cancerous and intraepithelial neoplasia) lesions and increased wi.th the serious degrees of lesions.Hybrid captureⅡtest can work ef- ficiently as a triage of patients with ASCUS,LSIL and HSIL before colposcopically directed biopsies.
