Progress in the study of Apelin-APJ system
- VernacularTitle:Apelin-APJ系统研究进展
- Author:
Chubing TAN
;
Guanhua DU
- Publication Type:Journal Article
- Keywords:
apelin;
APJ receptor;
heart failure;
regulation of blood pressure;
adipose tissue
- From:
Chinese Pharmacological Bulletin
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
The family of apelin peptides is derived from a single gene and activates the 7-transmembrane G-protein-coupled receptor,namely APJ.Apelins have been shown to be involved in the regulation of cardiovascular functions,fluid homeostasis,central nervous system functions,insulin sensitivity,food and water intake.The properties of this system may make it a novel drug target of therapeutic applications in the cardiovascular diseases such as hypertension and heart failure,and related diseases like obesity.
