Follow-up study on the pregnancy of an X-linked dominant Alport syndrome female
- VernacularTitle:一例X连锁Alport综合征女性妊娠期随访
- Author:
Hongwen ZHANG
;
Jie DING
;
Fang WANG
;
Huixia YANG
- Publication Type:Journal Article
- Keywords:
Nephritis,hereditary;
Pregnancy;
Follow-up studies
- From:
Journal of Peking University(Health Sciences)
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
SUMMARY Alport syndrome (AS) is a progressive renal disease characterized by hematuria and progressive renal failure. AS is a clinical and genetic heterogenous disease, X-linked dominant Alport syndrome(XLAS) is the major inheritance form. XLAS females have variable phenotypes, from microscopic hematuria to chronic renal failure. The effects of pregnancy course on pregnant woman and fetus were observed by follow-up study of an XLAS female. Results showed that pregnancy of the XLAS female was complicated by renal function deterioration, and fetal growth restriction. It suggests that the AS female with damaged renal function should be cautious in the choice of pregnancy.
