Clinical analysis of hematologic diseases complicated by pulmonary fungal infection
- VernacularTitle:血液系统疾病合并肺部真菌感染97例临床分析
- Author:
Jinguo BIAN
;
Ruobing GUO
;
Yun YAN
- Publication Type:Journal Article
- Keywords:
Hemotologic diseases;
Pulmonary infection;
Amphotericin B deoxycholate;
Itraconazole
- From:
Chinese Journal of Practical Internal Medicine
2006;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the clinical features,predisposing risk factors and treatment of hematologic diseases complicated by pulmonary fungal infection(PFI).Methods The medical records of 97 cases of PFI were retrospectively analyzed.Results Totally 201 fungal strains were obtained from 97 cases of hematologic diseases.The candida strains were 147(73.1%).Two-fungal infection was 17.5%,and secondary bacterial infection was 71.8%;relative death rate was 23.4%.Cure rate of Amphotericin B deoxycholate and Itraconazole was 67.7% and 63.7%.Conclusion Fungal infection is one of the main pathogens in hematologic diseases complicated by infection.Early diagnosis and treatment is the key to beneficial release and long time survival.Amphotericin B deoxycholate and Itraconazole were effective medicines for treated fungal infection.