Analysis of type 2 diabetic patients after a 3-year treatment
- VernacularTitle:2型糖尿病患者治疗3年前后临床疗效对比分析
- Author:
Xiaoai YAO
;
Zhangrong XU
;
Yuzhen WANG
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,non-insulin-dependent;
Metabolic control;
On the target
- From:
Chinese Journal of Practical Internal Medicine
2006;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare and analyze the metabolic control with the islet B cell function and the diabetic complications after a 3-year treatment in type 2 diabetic patients.Methods The T2DM patients were investigated who finished 3 years of treatment.The following measurements or determination was done:height,weight,waist,hips,blood pressure at standing and lying position,fasting glucose and insulin,glucose and insulin 2 h after taking food,HbA_1c,TC,TG,HDL-C,LDL-C,Cr,albuminuria and retinopathy.Results Totally 233 male and 178 female(56.53?10.33)yrs patients were analysized.The hypotensive,hypoglycemic and lipids agents were increased obviously and the number of the patients with insulin treatment increased too.HbA_1c was decreased,but no significant differences for the blood pressure and blood cholesterol,triglycerides after 3-year treatment.The fasting and post-meal insulin level,insulin resistance and the B-cell function index decreased significantly.Meanwhile,the patients with albuminuria and retinopathy increased from 15% and 26% to 23% and 33%.Conclusion Type 2 diabetic patients have not controlled the blood glucose,lipids and the blood pressure satisfactorily even if the agents for the blood sugar,lipids and blood pressure lowing are increased.Insulin resistance decreases but B cell function failure aggravates.The intensified therapy on the target should be paid more attention to.
