A rapid PCR method to determine the types of cyp2d6~*10 alleles
- VernacularTitle:快速测定cyp2d6~*10等位基因类型的PCR法
- Author:
Tao MA
;
Weimin CAI
;
Ying BU
;
Bing CHEN
;
Guohua ZHOU
- Publication Type:Journal Article
- Keywords:
PCR;
single nucleotide polymorphism (SNP);
cyp2d6~*10;
distribution frequencies of cyp2d610
- From:
Chinese Pharmacological Bulletin
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To establish a new simple, easy and economical PCR method for determining cyp2d6~*10 allele and studying its distributive frequencies in Chinese population. Methods The new PCR are established and compared with the classical PCR-RFLP. The 224 samples have been determined with the new PCR.Results the results of the two methods go on the way. The allele distribution frequencies of cyp2d6~*10 resembles the reports. Conclusion the new method is proved to be accurate and convenient. It provides a genetics basis for the drug therapy with individuals in clinics.
