Comparison study on improving lower limb ischemia by transplantation of antologous peripheral blood and bone marrow stem cells.
- VernacularTitle:自体外周血和骨髓干细胞移植对缺血性下肢血管疾病患者缺血状态改善的临床研究
- Author:
Xiaofeng YANG
;
Yanxiang WU
;
Hongmei WANG
- Publication Type:Journal Article
- Keywords:
Stem cell transplaotation,bone marrow,peripheral blood;
Ischemia;
Lower limbs
- From:
Chinese Journal of Practical Internal Medicine
2006;0(14):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Clinical efficacies of angiogenesis and improvement in lower limb ischemia are compared for the transplantation of both the peripheral blood stem cells(PBSC)and bone marrow stem cells(BMSC).Methods A total of 170 patients suffering from lower limb ischemia who received stem cell transplantation were monitored for random comparison study during September 2004 to October 2006.Among them 94 patients were treated with PBSC and 76 were BMSC.All the clinical data and laboratory findings before and after the transplantation in the 1st.12th and 24th weeks were comprehensively evaluated and tested by SPSS 12.0 software package.Results The total number of MNC,CD34+ cells and CD133+ cells in PBSC group was greatly more than BMSC group and had prominent or very prominent variances(P
