The clinical research of allogeneic hematopoietic stem cell transplantation using intravenous Bu/Flu conditioning regimen in the treatment of myeloid hematopathy
- VernacularTitle:静脉滴注白消安和氟达拉滨预处理方案行异基因造血干细胞移植治疗髓系血液病疗效观察
- Author:
Sanbin WANG
;
Dengming HU
;
Bo YIN
- Publication Type:Journal Article
- Keywords:
Hematopoietic stem cell transplantation,allogeneic;
Graft-versus-host disease;
Myeloid hematopathy;
Conditioning regimen
- From:
Chinese Journal of Practical Internal Medicine
2006;0(13):-
- CountryChina
- Language:Chinese
-
Abstract:
20?109/L in 12 to 19(median 14)days after transplantation.Complete chimerism was achieved in all the patients at one month after HSCT.Two patients had acute GVHD and one had chronic GVHD.With a median follow-up of 31(19~37)months,8 of 9 patients were alive and disease-free.Conclusion The intravenous Bu/Flu conditioning regimen may reduce transplantation-related toxicities and can achieve full chimerism and high long-term disease-free survival.Allogeneic hematopoietic stem cell transplantation using intravenous Bu/Flu conditioning regimen is a safe and effective option for the patients with myeloid hematopathy.
