Potential of Co-culture Induction in Antibiotics Discovery from Bacteria-associated with Marine Sponge Hymeniacidon perleve
- VernacularTitle:共培养海绵微生物诱导抗菌活性物质的研究
- Author:
Pengfei GUO
- Publication Type:Journal Article
- Keywords:
Hymeniacidon perleve,Sponge-associated microorganism,Co-culture,Induction,Antimicrobial activity
- From:
Microbiology
1992;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
Ten actinomycetes strains from inter-tidal marine sponge Hymeniacidon perleve of China Yellow Sea were isolated and bio-assayed for antibiotic activities.3 of the 10 strains displayed antimicrobial activity when in monoculture.While strain Hp-053 was co-cultured with each of the other 9 strains,5 of the 9 co-cultures exhibited enhancing antimicrobial activity.TLC results and bio-autography of extracted samples indicated that chemical compounds and antimicrobial compounds produced by co-cultures of sponge associated actinomycetes were different from those by monoculture.Co-culture induction may be a valuable novel tool for the exploitation of sponge associated microorganism.
