Distribution of ER? in sigmoid colon specimens of slow transit constipation
- VernacularTitle:慢传输型便秘患者乙状结肠雌激素?受体分布的免疫组化观察
- Author:
Lin ZHANG
;
Baohua LIU
;
Weidong TONG
- Publication Type:Journal Article
- Keywords:
slow transit constipation;
ER?;
interstitial cells of Cajal
- From:Journal of Third Military Medical University
2002;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the distribution of ER? in the sigmoid colon specimens from the patients with slow transit constipation(STC).Methods The expression of ER? was detected by immunohistochemical staining in formalin-fixed,paraffin-embedded sigmoid colon tissues from 16 cases of STC,and from 8 cases of rectal cancer at Dukes' stage A,2 cases of rectal villous adenoma(10 as control).The positive cells were analyzed by computer assistant image analysis system.Results ER? immunoreactivity was present in normal epithelium and interstitial cells of the sigmoid colon tissues in the two groups,but nucleus-positive in STC group and cytoplasm-positive in control group.In comparison with the control group,the ER? immunoreactivity in STC group was much lower(P
