Effect of compounds extracted from spatholobus suberectus dunn on the proliferation of hematopoietic progenitor cell
- VernacularTitle:鸡血藤单体化合物对造血祖细胞增殖的调控作用研究
- Author:
Ping LIU
;
Dongxiao WANG
;
Guiyun CHEN
;
Mengli CHEN
- Publication Type:Journal Article
- Keywords:
spatholobus suberectus dunn (SSD);
catechin;
serum pharmacology;
hematopoietic progenitor cell (HPC);
CFU-GM;
CFU-E;
BFU-E;
CFU-Meg
- From:
Chinese Pharmacological Bulletin
1986;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To study effects of nine compounds extracted from Spatholobus suberectus Dunn (SSD) on proliferation of hematopoietic progenitor cell (HPC) in marrow-depressed mice. Methods Serum pharmacology experiment was used to observe the influence of nine compounds on growth of CFU-E、BFU-E、CFU-GM、CFU-Meg in marrow-depressed mice. Results Compared with the control, all compounds except pyromucic acid and ononin could significantly stimulate the growth of CFU-GM (P