Effect of extended-release methylphenidate on the ecological executive function for attention deficit hyperactivity disorder
- VernacularTitle:哌甲酯控释剂对注意缺陷多动障碍患儿生态学执行功能的影响
- Author:
Ying QIAN
;
Qingjiu CAO
;
Yufeng WANG
- Publication Type:Journal Article
- Keywords:
Attention deficit disorder with hyperactivity;
Methylphenidate;
Executive function;
Ecology
- From:
Journal of Peking University(Health Sciences)
2004;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To test the effect of extended-released methylphenidate(Concerta) on ecological executive function for attention deficit hyperactivity disorder(ADHD) and to evaluate the correlation between the improvement of ecological executive function and that of the core symptom of ADHD.Methods:We conducted a 4-6-week open-trial study of extended-released methylphenidate(18-54 mg/d) in 26 children with ADHD,aged 8-14 years.Ecological executive function and ADHD symptoms were ascertained by the parent form of behavior rating inventory of executive function(BRIEF),ADHD-Ⅳ rating scale and Conners short form rating scales before and after the treatment.Results:The mean item raw score of global executive composite(GEC),metacognition index(MI),working memory,monitor and inhibition subscale of BRIEF were significantly decreased after the treatment(t=2.763-3.380,P