Isolation of Haemophilus aphrophilus and Coagulase-Negative Staphylococci from the Blood of a Patient with Prosthetic Valve Endocarditis.
- Author:
Chang Ki KIM
1
;
Injoo CHO
;
Youn Hee PARK
;
Kyoung Ho ROH
;
Dongeun YONG
;
Kyungwon LEE
;
June Myung KIM
;
Yunsop CHONG
Author Information
1. Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea. deyong@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Haemophilus aphrophilus;
Coagulase-negative staphylococci;
Endocarditis
- MeSH:
Adult;
Aggregatibacter aphrophilus*;
Ampicillin;
Anti-Bacterial Agents;
Bacillus;
Bacteria;
Brain Abscess;
Cefotaxime;
Ceftriaxone;
Endocarditis*;
Female;
Gentamicins;
Haemophilus*;
Humans;
Korea;
Oxacillin;
Peritonitis;
Pneumonia;
Sepsis;
Teicoplanin;
Vancomycin
- From:Korean Journal of Clinical Microbiology
2006;9(1):71-75
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Haemophilus aphrophilus is a facultative anaerobic, gram-negative coccobacillus or bacillus and its growth is stimulated by 5 to 10% CO2. Most Haemophilus species require either exogenous X or V factor or both to grow, but H. aphrophilus can grow without these factors. H. aphrophilus rarely causes invasive infections such as endocarditis, septicemia, pneumonia and peritonitis in human. Two cases of infective endocarditis by H. aphrophilus have been reported in Korea. However, there has been no report of polymicrobial endocarditis by H. aphrophilus and other bacteria. We isolated H. aphrophilus and coagulase-negative staphylococci (CNS) from the blood of a 38-year-old woman with prosthetic valve endocarditis. She underwent an emergent operation and a culture of the prosthetic valve grew H. aphrophilus. Brain abscess was developed at hospital day 11. H. aphrophilus was susceptible to all antibiotics tested such as ampicillin and cefotaxime, and CNS was susceptible to oxacillin and vancomycin. The patient responded well to therapy with ceftriaxone, teicoplanin, and gentamicin.
