Application of total parenteral nutrition with alanyl-glutamine dipeptide in postoperative patients of gastrointestinal neoplasms
- VernacularTitle:丙氨酰谷氨酰胺双肽全肠外营养在胃肠道肿瘤患者术后的应用
- Author:
Xianju ZHANG
- Publication Type:Journal Article
- Keywords:
alanyl-glutamine;
TPN;
gastrointestinal neoplasms
- From:Journal of Third Military Medical University
2003;0(11):-
- CountryChina
- Language:Chinese
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Abstract:
Objective To investigate the application of total parenteral nutrition with alanyl-glutamine dipeptide in postoperative patients of gastrointestinal neoplasms.Methods Sixty-four postoperative patients of gastrointestinal neoplasms were randomly divided into study group and control group.The patients in the two groups all received isocaloric(96.0 kJ?kg-1?d-1)and isonitrogen(0.25 g?kg-1?d-1)parenteral nutrition from postoperative day 1 to day 7,and the study group received additional alanyl-glutamine.The serum levels of albumin,pre-albumin,IgG,IgA,IgM,C3,C4 were measured before operation and on postoperative day 1 and 8.Nitrogen balance was calculated on postoperative day 1,4 and 8.Results Compared with preoperation,the serum levels of albumin and pre-albumin were both significantly decreased in two groups(P