HIV drug resistance and influence factors in some provinces of China
- VernacularTitle:中国部分地区人免疫缺陷病毒耐药及其影响因素分析
- Author:
Min ZHANG
;
Qinghai HU
;
Hua CHENG
- Publication Type:Journal Article
- Keywords:
HIV;
Drug resistance;
Compliance;
Treatment
- From:
Chinese Journal of Practical Internal Medicine
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To prevent the prevalence of drug resistance viruses,we analyzed drug resistance mutations of HIV-1 among HIV-1 infected individuals in seven provinces of China.Methods We acquired 718 HIV-1 infected patients' treatment and compliance from questionnaires,amplified HIV-1 pol genes by RT-PCR and nest-PCR,sequenced RT and protease regions and run clustal with the subtype B consensus amino acid sequence in Stanford HIV drug resistance sequence database.Results The viral load in treated patients was obviously lower than that in untreated patients(P
