CD34 expression and microvessel density in liver tissue from fibrotic patients with Schistosoma japonicum infection
- VernacularTitle:日本血吸虫病肝纤维化患者肝组织CD34表达和微血管密度测定的临床意义
- Author:
Jialin CHEN
;
Xiaowei WEN
;
Ning LU
;
Yanping ZHANG
;
Wei WANG
;
Hongjie YANG
- Publication Type:Journal Article
- Keywords:
Schistosomiasis japonica;
Hepatic fibrosis;
Liver sinusoid;
CD34;
Microvessel density
- From:
Chinese Journal of Schistosomiasis Control
1989;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between CD34 expression or microvessel density and hepatic fibrosis degree in advanced schistosomiasis patients.MethodsThirty-five advanced schistosomiasis patients and 5 control patients were included in this study.CD34 expression in liver tissue was measured with immunohistochemistry while microvessel density(MVD)of liver tissue was evaluated under a light microscope.ResultsCD34 expression and MVD value were significantly correlated with hepatic fibrosis degree in liver tissue from the advanced schistosomiasis patients.ConclusionsCD34 expression and MVD value are two histological parameters representing the liver sinusoid changes during fibrogenesis in advanced schistosomiasis patients.
