Inactivation and detoxification of pertussis vaccine by 0.1% formalin: Preliminary results
- Author:
Phan Thi Tuyet
- Publication Type:Journal Article
- Keywords:
pertussis vaccine
- MeSH:
Pertussis Vaccine;
vaccines;
Whooping Cough
- From:Journal of Preventive Medicine
2003;13(1):31-33
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Using 0.1% formalin for inactivation and detoxification in the production of pertussis vaccine gave good results with 3 experimental lots PM10, PM11, and PM12 had high safety: MWG test was 76%-84.2% higher than control lots 62.4%, LPF test was 32,210-41,200 lower than control lot 58,600. The preliminary findings suggest these 3 experimental lots had less toxicity than standard and control lot. This method can be used in routine pertussis vaccine production
