EFFECT OF VITAMIN A SUPPLEMENTATION ON THE LEVEL OF IgG ANTIBODY TO MEASLES STRENGTHENED VACCINATION
- VernacularTitle:补充维生素A对接种麻疹疫苗的学龄儿童IgG抗体水平的影响
- Author:
Guoxian HUANG
;
Yixiang SU
;
Liming LU
;
Hai LIN
;
Yanheng WU
;
Bo SHU
- Publication Type:Journal Article
- Keywords:
vitamin A;
measles;
vaccination
- From:
Acta Nutrimenta Sinica
1956;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the relationship between vitamin A (VA) supplementation and the level of IgG antibody to measles strengthened vaccination. Method: Fifty-three school children aged 5-13 years were selected as the test group of VA supplementation, and fifty-two school children as the control group whose ages and sex matched with the test group. The test group was supplicd po the VA pills (2 500IU) at the same time with measles strengthened vaccination for one month. The level of serum VA was analyzed by HPLC. Measles antibody IgG was detected by ELISA. Results: One month after VA supplementation, sernm VA in test group was 376.5?74.2 ?g/L, showing statistical increase over before. The positive rates of measles antibody in the test group were increased from 69.8% to 100%, and the protective rate from 5.6% to 60.4%. The positive rates of measles antibody in the control group were increased from 71.2% to 100%, and the protective rates from 0% to 17.4%. The protective rate in the test group was statistically higher than the control. Conclusion: Simultaneous VA supplementation (especially for the children of VA deficiency) and measles strengthened vaccination contribute to the increase of measles antibody IgG in school children.
