Studies on ultrasonography and Doppler velocity tracing of common carotid artery in obstructive sleep apnea hypopnea syndrome in a porcine model
- VernacularTitle:阻塞性睡眠呼吸暂停低通气综合征模型猪颈总动脉超声和多普勒流速曲线实验研究
- Author:
Yongyi LIU
;
Xiang SHENG
;
Ye XU
- Publication Type:Journal Article
- Keywords:
ultrasonography,Doppler;
sleep apnea,obstructive;
carotid artery,common;
models,animal
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the morphologic changes and hemodynamic parameters of the common carotid artery in obstructive sleep apnea hypopnea syndrome(OSAHS)in a porcine model using ultrasound and color Doppler.Methods A total of 12 pigs were randomly divided into model group and control group(n=6 for each).All pigs were fed under the same conditions with exception of th ose in the model group which were kept in a hypobaric chamber for experiments.The parameters of systolic velocity(S)and diastolic velocity(D),resistant index(RI)and S/D in Doppler as well as maximum IMT(intima-media thickness)with two-dimensional ultrasound were obtained in the carotid artery of all animals were determined,and the latter was confirmed by animal dissection when the symptoms of OSAHS appeared in the model group.Results The diameter of the lumen of the common carotid artery in model group(3.18?0.17)was smaller than that of control group(3.47?0.15,P