Clinical observation and treatment for 189 patients with acute lung injury (ALI) after liver transplantation
- VernacularTitle:肝脏移植术后急性肺损伤患者的临床观察与处理
- Author:
Guosheng DU
;
Bingyi SHI
;
Ming CAI
- Publication Type:Journal Article
- Keywords:
liver transplantation;
respiratory distress syndrome,adult;
ICU
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To further probe and investigate the etiopathogenisis of acute lung injury(ALI)after in situ liver transplantation,and to search for an effective treatment.Methods ALI was final diagnosed as the oxygen saturation index(OSI)was less than 200.The arterial blood gas analysis and others clinical examinations were timely monitored to 189 of 211 patients undergone liver transplantation in situ.The other 22 cases died of other causes at the early stage after liver transplantation.The occurring of ALI was analyzed correlatively with protopathy.All the patients were given with the therapies of oxygen,antibiotics,immunosuppressant,drugs of liver protection,nutrition,diuretics,and vasodilators,and some criteria were measured continuously.The oxygen concentration and circulation volume were adjusted accordingly with blood gas analysis and central venous pressure respectively.Results ALI occurred within 146 of 189 patients(77.5%)at the early stage after liver transplantation in situ.All the cases were treated systemically and recovered to normal.The liver function kept unvaried during the period of treatment.By analyzing the patients' data,the occurrence of ALI showed a definite relation to the hepatic decompensation of patients' primary disease,the blood loss during operation,and to the liquid intake/output postoperation.Conclusion For the purpose of preventing or reducing the incidence of ALI,It is important to pay attention to the primary disease,keep stability of the blood dynamics of the patients during or after operation.Besides the oxygen therapy,systemic general treatment is also necessary for those patients who received in situ liver transplantation.
