Expression of COX-2 in gastric cancer and gastritis and its relationship with HP
- VernacularTitle:环氧化酶-2在胃癌和胃炎中的表达及其与幽门螺杆菌感染的关系
- Author:
Hongju LI
;
Hao TANG
;
Min JIANG
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Gastritis;
COX-2;
Helicobacter pylori
- From:
Chinese Journal of Practical Internal Medicine
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study HP infection and expression of COX-2 in gastric cancer and gastritis in order to investigate the change of COX-2 in the development of gastric cancer and the role of HP infection in the expression of COX-2.Methods A total of 180 biopsy samples from December 2004 to April 2005 were collected.We use immunohistochemistry technology to study HP infection and expression of COX-2 in gastric cancer and gastritis.Results The level of COX-2 expression in gastric cancer and atrophic gastritis complicated with dysplasia was significantly higher than in superficial gastritis(P
