Cardiovascular effects of Angiotensin(1-7)
- VernacularTitle:血管紧张素(1-7)的心血管效应
- Author:
Jun DU
;
Changxun CHEN
- Publication Type:Journal Article
- Keywords:
angiotensin(1-7);
angiotensinⅡ;
angiotensin-converting enzyme
- From:
Chinese Pharmacological Bulletin
1986;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Angiotensin (1-7) is an important biologically active substance of the renin-angiotensin-aldosterone system.It has vasodilatory,antiproliferative and antithrombotic effects.The functions of Ang (1-7) are often opposite to Ang Ⅱ. Ang (1-7) can be formed from Ang Ⅰ or Ang Ⅱ .Angiotensin-converting enzyme 2 is the rate-limiting enzyme of Ang(1-7).The biological effects of Ang (1-7) are mainly mediated by its receptor, the G-protein-coupled receptor Mas.