Clinical analysis of preventing the progress of chronic serious hepatitis B with Lamivudine during the short-term
- VernacularTitle:拉米夫定短期内阻断重度慢性乙型肝炎进展的临床分析
- Author:
Ying XIONG
;
Yaofen WANG
- Publication Type:Journal Article
- Keywords:
Chronic serious hepatitis B;
Lamivudine
- From:
Chinese Journal of Practical Internal Medicine
2006;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Lamivudine therapy in preventing disease progression in patients with the chronic serious hepatitis B during the short-term. Methods 40 patients with the chronic serious hepatitis B, who have the trend of developing severe hepatitis,were randomized into treating group(n=20) and control group (n=20).The two groups were given the same synthetic treatment. Treating group was given Iamivudine 100mg daily in addition, for 8 weeks. Effects were assessed by clinical , biochemical , the incidence of chronic severe hepatitis,suvival rates and virologic parameters. Results (1) After 8-weeks treatment , the incidence of chronic severe hepatitis in treating group was lower than in control group(X~2=4. S1 ,P
