Study on Defecation Promoting Effect of Emodin Capsule on Constipation Model
- VernacularTitle:大黄素胶囊促进便秘模型排便作用研究
- Author:
Xiping ZHANG
;
Qihui CHENG
;
Ying WANG
- Publication Type:Journal Article
- Keywords:
Emodin;
Constipation effect;
Empirical study
- From:
Journal of Medical Research
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of emodin capsule on constipation model mice caused by diphenoxylate and compare it with the effect of Rhubarb & sodium bicarbonate tablet.Methods The ICR mice were divided into 6 groups as blank control group, diphenoxylate model group, emodin 25mg/kg,50mg/kg,100mg/kg group, and Rhubarb & sodium bicarbonate tablet 500mg/kg group. The blank control group and model group were given distilled water intragastrically while the rest 4 groups were given certain doses. The time of first dark stool defecation and 6-hour defecation quantity of each mouse were observed and recorded. The total weight of stool was weighed.Results The time of first dark stool defecation of the model group is markedly longer than that of control group (P
