Clinical study of plasma homocysteine, serum folic acid and vitamin B_(12) in ischemic leukoaraeosis
- VernacularTitle:缺血性脑白质疏松症患者血浆同型半胱氨酸、血清叶酸及维生素B_(12)水平的变化
- Author:
Xianfeng LIU
;
Guohua ZHANG
- Publication Type:Journal Article
- Keywords:
leukoaraiosis;
cysteine;
folic acid;
vitamin B 12
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical importance and the relationship between the levels of plasma total homocysteine (Hcy), serum folic acid and vitamin B 12 , and the occurrence and development of ischemic leukoaraeosis (LA). Methods Ischemic LA group and normal control group with 100 cases for each were studied. The 100 cases in ischemic LA group were firmly diagnosed by CT or / and MRI. The levels of plasma total Hcy, serum folic acid and vitamin B 12 of the patients in ischemic LA group were measured, and compared with that in control group. Results The level of plasma Hcy in ischemic LA group (19.79?5.25?mol/L) was significantly higher than that in control group (12.02?2.11?mol/L), while the levels of serum folic acid and vitamin B 12 in ischemic LA group (2.08?0.84ng/ml and 140.13?45.49pg/ml) were lower than that in control group (4.39?1.30ng/ml, 297.45?120.23pg/ml). The differences between two groups were statistically significant (P
