Study on bio-dynamic equation for gene regulation networks
- VernacularTitle:基因调控网络建立的生物动力学方程研究
- Author:
Ling LIU
;
Dong YI
- Publication Type:Journal Article
- Keywords:
gene regulation network;
Lotka-Volterra equation;
yeast gene expression
- From:Journal of Third Military Medical University
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore a new bio-dynamic differential equation to establish gene regulatory network based on the time-space of gene expression.Methods According to bio-dynamic competitive model and differential equation,a new time-space Lotka-Volterra differential equation was established and was applied to time-order expression data.Results The model was applied to set up the regulation network of yeast genes.The regulatory relation was found and compared with the experiment results.Conclusion The results from the new model were almost consistent with the real situation.So this model can remedy the shortage of other models.It's a new valuable differential equation model.
