The association between breast carcinoma and columnar alteration with prominent apical snouts and secretions
- VernacularTitle:伴有显著顶浆分泌柱状变化的乳腺导管上皮病变与乳腺癌的关系
- Author:
Weiqiang ZHENG
- Publication Type:Journal Article
- Keywords:
breast neoplasms;
core needle biopsy;
columnar alteration with prominent apical snouts and secretions
- From:
Academic Journal of Second Military Medical University
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the pathological characteristics of columnar alteration with prominent snouts and secretions (CAPSS) and its relationship with incidence of breast carcinoma. Methods: One hundred forty-four CAPSS specimens identified by breast core needle biopsies (CNB) were retrospectively evaluated. The CAPSS specimens were subdivided into lesions with (n=108) and without (n = 36) atypical ductal hyperplasia and their pathological findings were compared. Results: In situ and invasive carcinomas were found in 21. 5% (31/144) of the specimens, including those with and without atypical hyperplasia. We also found that specimens with atypical hyperplasia had a higher malignant incidence than those without atypical hyperplasia (P = 0. 001). Conclusion: CAPSS, especially when with atypical ductal hyperplasia, are associated with breast carcinoma.
