Influence of Daotan Decoction on Nonalcoholic Steatohepatitis in Rats
- VernacularTitle:导痰汤对大鼠非酒精性脂肪性肝炎的影响
- Author:
Hao YING
;
Hancheng CHENG
;
Yanwu LI
;
Ling LI
- Publication Type:Journal Article
- Keywords:
Nonalcoholic steatohepatitis;
Rat;
Daotan decoction;
Animal experiment
- From:
Journal of Medical Research
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the Influence of Daotan decoction on nonalcoholic steatohepatitis (NASH) in Rats, and its relative mechanisms was analyzed. Methods The rat nonalcoholic steatohepatitis model was induced by high fat diet. The rats of therapeutic groups were treated with small, middle and high dose Daotan decoction respectively. Their general condition, liver index, and the fat change and inflammation of liver were observed. The serum ALT、triglyceride(TG), total cholesterol(TCH), low density lipoprotein(HCL-C), high density lipoprotein(LDL-C)were determined respectively. Results The liver index of therapeutic groups were markedly reduced respectively compared with those of model group(P0.05). The liver inflammation in therapeutic groups were improved better those in model group(P
