Inhibitory effect of ibandronate on the growth of lung cancer cell line PLA-801D in vitro
- VernacularTitle:伊班膦酸钠对人肺巨细胞癌高转移株PLA-801D体外生长的抑制作用
- Author:
Guanghai DAI
;
Zhiyong WU
;
Shunchang JIAO
- Publication Type:Journal Article
- Keywords:
ibandronate;
bisphosphonate;
lung neoplasms;
cell cycle
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the inhibitory effect of ibandronate(IBN)on the growth of lung cancer cell line PLA-801D in vitro,and the mechanism of such effect was studied.Methods The effects of different doses or treatment time of IBN on the growth of PLA-801D cell line were detected by MTT method.The mechanism of the effect was analyzed by the examination of cell cycle using flow cytometry.Results With the concentration of 10 to 100 ?g/ml,IBN obviously inhibited the growth of PLA-801D cell(P
