Maternal Characteristics, Short Mid-Trimester Cervical Length, and Preterm Delivery.
10.3346/jkms.2017.32.3.488
- Author:
Soo Hyun CHO
1
;
Kyo Hoon PARK
;
Eun Young JUNG
;
Jung Kyung JOO
;
Ji Ae JANG
;
Ha Na YOO
Author Information
1. Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. pkh0419@snubh.org
- Publication Type:Original Article
- Keywords:
Mid-Trimester;
Preterm Birth;
Obstetric History;
Prior Cervical Excisional Procedure;
Short Cervical Length;
Sonographic Cervical Length
- MeSH:
Cervix Uteri;
Cohort Studies;
Female;
Gestational Age;
Humans;
Logistic Models;
Maternal Age;
Parity;
Pregnancy;
Premature Birth;
Retrospective Studies;
Term Birth
- From:Journal of Korean Medical Science
2017;32(3):488-494
- CountryRepublic of Korea
- Language:English
-
Abstract:
We aimed to determine the maternal characteristics (demographics, an obstetric history, and prior cervical excisional procedure) associated with a short mid-trimester cervical length (CL, defined as a CL of ≤ 25 mm) and whether having a short cervix explains the association between these maternal characteristics and spontaneous preterm delivery (SPTD, defined as a delivery before 34 weeks). This is a single-center retrospective cohort study of 3,296 consecutive women with a singleton pregnancy who underwent routine CL measurement between 20 and 24 weeks. Data were collected on maternal age, weight, height, parity, obstetric history (nulliparity; a history of at least 1 SPTD; and at least 1 term birth and no preterm birth [low-risk history group]), and prior cervical excisional procedure. In the multivariate regression analysis, an obstetric history, prior cervical excisional procedure, and gestational age at measurement were the variables significantly associated with short CL. In contrast, maternal weight, height, age, and parity were not significantly associated with short CL. By using the likelihood of SPTD as an outcome variable, logistic regression indicated that short CL and obstetric history, but not prior cervical excisional procedure, were significantly associated with SPTD after adjustment for potential confounders. A history of SPTD and prior cervical excisional procedure were associated with an increased risk of a short mid-trimester CL. A history of SPTD, but not prior cervical excisional procedure, is associated with an increased risk of SPTD, independent of a short CL.